ARE DELTA-8 GUMMIES SAFE?

ARE DELTA-8 GUMMIES SAFE?

Delta 8 THC is a relatively new hot topic in the cannabis market. As with any new product, it raises the question, “Is delta 8 THC safe?”  Scientific research is being conducted to cover its properties, and the risks associated with this new cannabinoid may be unclear.

In contrast to delta-9-THC, delta-8-THC has a slightly lower psychoactive potency. Although delta-8-THC has been used extensively in SAR studies on other cannabinoids, few studies on its bioactivity have been conducted. It is likely an artifact of THC degradation rather than a plant metabolic artifact. It increased food consumption more than THC at low concentrations while maintaining animal performance and activity. As a result, it may contribute to the ‘munchies,’ a term used to describe a Cannabis-induced appetite increase. Krowicki (2012) noted that in rats, delta-8-THC suppressed behavior by activating the arachidonic acid cascade via the CB1 receptor. This could be a useful model for studying human motivation and be used to understand drug dependencies.

Delta-8-THC Safety Studies

Currently, delta-8 safety studies are limited. Abrahamov et al. (1995) argued for the use of Delta 8 on chemo-treated kids. The delta-8 derivative reduced treatment-induced nausea. Only two kids reported ‘euphoria’ and irritability. It is difficult to quantify ‘euphoria’ in children, as noted by the study researchers. According to Simonian et al. (2020), the drug’s only recent safety study ended in 2009 during phase two of the clinical trial. Since then, no concrete clinical trial results have emerged. Because the government restricts cannabis and hemp research. Also, in this study, patients receiving moderately emetogenic chemotherapy were compared to those using delta-8 THC. The results were not published because the study was halted. Only a few research papers discussed the clinical trial’s effects on humans. The safety of delta-8 THC was never discussed. Based on a 1995 study, delta-8 THC may be used to treat nausea. Scientists say delta-8 THC is less sedating, more energizing, and may help improve appetite. Still, all of the claims about delta-8’s potential seem speculative and unfounded.

Kruger& Kruger (2021), compared the effects of oral and intravenous administration of delta-8 and delta-9 THC on adult males. Oral delta-8 THC had cannabis-like effects on perception and the body. In coordination, dry mouth, dizziness, and visual distortions were observed. The intravenous side effects were similar to delta-9 THC but milder. Thus, the researchers estimated delta-8 THC potency as 2:3.

Is Delta-8-THC Safe?

When it comes to the safety profile of delta-8 THC, personal experiences provide the majority of the evidence. There have been no long-term studies on the derivative or its effect. This scarcity of research makes it even more difficult to draw firm conclusions about the safety of delta-8 THC. Delta-8, on the other hand, appeals to a wide range of people, including cannabis companies, medical scientists, and cannabis users.  A New York company recently launched therapeutic delta-8 gummies, delta-8 THC, with a broad therapeutic window.

The product has positive effects, and the side effects are infrequent enough to be noticed. Compared to delta-9 THC. Delta et al (2021) showed that delta-8 binds to CB1 receptors and prevents users from becoming paranoid. Delta-8 is also delivering on safety because it is still federally legal. This means that more research is needed before making a final decision on the product. ALSUntangled Group (2012), noted that delta-8 is not potent enough to cause a lethal overdose. Moreover, it cannot get you as high as delta-9 THC; delta-8 may not have any negative effects on the body after use. One quickly builds a tolerance to delta-8’s short-lived high, making it less appealing as a recreational drug. As a result, it is quite impossible to quantify the substance’s long-term effects. Furthermore, it was stated that users only develop a habitual addiction in which they crave the high feeling, but this is not how alcoholism develops. This means that users will never become so reliant on the drug that it interferes with their finances, relationships, or mental health when they are not taking it.

Some Possible Short-Term Side Effects of Delta-8 Gummies

A few short-term side effects are associated with delta 8 THC, but they are similar to those associated with delta 9 THC. Tetrahydrocannabinol affects everyone differently, and some people may be more sensitive to its cognitive effects than others. Some of the possible short-term side effects include:

  • Dry mouth
  • Dizziness
  • Nausea
  • Physical discombobulation
  • Difficulty in physical coordination.

Most people will experience at least one or two side effects, the most common of which are dry mouth and physical distortion. However, they are minor and are more nuisance than a genuine threat to your health. Nonetheless, these symptoms may worsen over time; if this occurs, discontinue the use of delta 8 THC until the symptoms subside.

Possible Long-Term Effects of Delta-8 Gummies

Research is scarce regarding the long-term risks of delta 8 THC. It has the same side effects as delta 9 THC because they are both tetrahydro cannabinoid compounds. According to Lisdahl et al (2014), young people may be at a higher risk of developing behavioral addiction. This is because their brains are still developing, and as such, they are more susceptible to the cognitive effects of delta 8 THC. Those under the age of 21 should abstain from all forms of THC. The following are the main long-term risks associated with delta 9 THC, and probably also with delta 8 THC

  • Deficiency in individual attention span.
  • Acute psychosis
  • Dependency and addiction
  • Short-term memory loss

Although the risks listed above may appear frightening, it is important to note that research is limited, so most of these side effects are only hypothetical. Some people report experiencing these long-term effects, particularly heavy use, but this may not be the case with delta 8 THC. It’s worth noting that everyone reacts differently to THC and other substances once more. Some people may not notice any side effects, whereas others may. In many cases, these effects fade after a long period of abstinence. Although research is still in its early stages, the long-term risks associated with delta 8 THC are considered minor.

Conclusion

When used responsibly, delta 8 THC is relatively safe. But, like any other substance, it comes with some risks. More research is required to determine the long-term effects and risks of delta 8 THC. Unlike other cannabinoids, delta 8 appears to be safe for consumption. Buying delta 8 THC gummies from reputable vendors who publish relevant lab reports can help you avoid the potential risks of using contaminated hemp extracts.

References

Abrahamov, A., Abrahamov, A., & Mechoulam, R. (1995). An Efficient New

Cannabinoid Antiemetic In Pediatric Oncology. Life Sciences, 56(23-24), 2097-2102.

Alsuntangled Group. (2012). Alsuntangled No. 16: Cannabis. Amyotrophic Lateral

Sclerosis, 13(4), 400-404.

Delta, D., Ages, T. C. V. C., & So Inaccurate, W. A. C. (2021). CBD Oracle Lab Study

Shows Some Delta-8 Products Are 7700% Over The Legal Delta-9 THC Limit. We Got 51 Hemp-Derived Delta-8 THC Products Tested By An Independent Lab, And Found High Levels Of Delta-9 THC In Most Of Them. And That Was Just The Beginning. Delta.

Krowicki, Z. K. (2012). Involvement Of Hindbrain And Peripheral Prostanoids In

Gastric Motor And Cardiovascular Responses To Delta-9-Tetrahydrocannabinol In The Rat. J Physiol Pharmacol, 63(6), 581-8.

Kruger, D. J., & Kruger, J. S. (2021). Consumer Experiences With Delta-8-THC: Medical

Use, Pharmaceutical Substitution, And Comparisons With Delta-9-THC. Cannabis And Cannabinoid Research.

 A Critical Narrative Review Of Medical Cannabis In Pediatrics Beyond Epilepsy, Part

III: Chemotherapy-Induced Nausea And Vomiting And Inflammatory Bowel Disease. Pediatric Medicine, 3.

Lisdahl, K. M., Wright, N. E., Medina-Kirchner, C., Maple, K. E., & Shollenbarger, S.

(2014). Considering Cannabis: The Effects Of Regular Cannabis Use On Neurocognition In Adolescents And Young Adults. Current Addiction Reports, 1(2), 144-156.

Simonian, J., Varanasi, S., Richards, G., Van Nguyen, A., Diaz-Fong, J. P., & Le, J. (2020).

A Critical Narrative Review Of Medical Cannabis In Pediatrics Beyond Epilepsy, Part III: Chemotherapy-Induced Nausea And Vomiting And Inflammatory Bowel Disease. Pediatric Medicine, 3.

MS, University of Tartu
Sleep specialist

Using the acquired academic and professional experience, I advise patients with various complaints about mental health - depressed mood, nervousness, lack of energy and interest, sleep disorders, panic attacks, obsessive thoughts and anxieties, difficulty concentrating, and stress. In my free time, I love to paint and go on long walks on the beach. One of my latest obsessions is sudoku – a wonderful activity to calm an unease mind.

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