Apetamin is a supplement used widely to boost weight gain and stimulate appetite. It contains lysine and cyproheptadine as its main ingredients.

The majority of people struggle tirelessly to lose weight. However, some wish they had a healthy weight and shape. In short, they are also struggling to gain weight. In search of quick results to gaining weight, they may turn web pages upside down. Apetamin is just one of the best supplements you can use to pull up your weight. It is commonly used by women than by men, as it has been said that helps them get the perfect curves and breasts.However, apetamin is not regulated by Food and Drug Administration (FDA) and its use may as well warrant some health problems.This article explains everything about apetamin.

What Is Apetamin?

Simply put, apetamin is a supplement that is made specifically for weight gain. Apetamin was designed in India by a pharmaceutical company called TIL Healthcare PVT. It is primarily a vitamin containing lysine and cyproheptadine.The manufacturer’s label states that in every 5 ml or 1 teaspoon of Apetamin syrup, there are the following vitamins:2 mg of cyproheptadine hydrochloride, 150 mg of L-lysine hydrochloride, 1 mg of vitamin B6 (pyridoxine hydrochloride), 2 mg of vitamin B1 (thiamine hydrochloride), 15 mg of vitamin B5 (nicotinamide), and 4.5 mg of a lesser form of vitamin B5 (dexpanthenol).

According to a study by the National Center for Biotechnology Information, cyproheptadine, lysine, and vitamins can potentiate weight loss. Cyproheptadine hydrochloride helps stimulate appetite significantly as a side effect. Based on another study published in PubMed, the human body when under allergic reactions, can make histamine which is a chemical responsible for inflammation of mucous membranes, hives, runny nose, and teary eyes. To counteract or inhibit histamine’s action, cyproheptadine hydrochloride is administered.

As a supplement, apetamin is sold in form of syrup which contains all the mentioned vitamins and lysine, or a tablet that contains cyproheptadine hydrochloride only.It is illegal to buy and sell the supplements of apetamin in the United States. This is because it is not approved by FDA as it is deemed not safe for use.

Mode of Action of Apetamin

The main side effect of cyproheptadine hydrochloride is increased appetite. For this reason, it is easy to gain weight with the use of Apetamin supplements. Studies are still being carried out on how cyproheptadine increases appetite, but still, there are a few proposed theories.

One way cyproheptadine hydrochloride works is by stimulating the production of insulin-like growth factor (IGF-1) when it was given to underweight children. This type of hormone is thought to induce weight gain.Another way is by interacting with the hypothalamus. This is a small part of the brain that is responsible for balanced appetite, hormones regulation, and intake of food among others.

L-lysine, an amino acid in Apetamin has been found to increase appetite in some animal studies. Though this is not clear if it can work the same way on human.

Is Apetamin Effective For Weight Gain?

Valid research on Apetamin and weight is lacking, but researchers strongly think that the main ingredient of Apetamin, that is, cyproheptadine hydrochloride may help increase appetite. This works better in people who have lost and may be inching closer to getting malnourished. With an increased and regular meal intake, one can easily add weight.

One study published in PubMed examined 16 children diagnosed with cystic fibrosis for 3 months. Cystic fibrosis is usually passed from parents to children and presents with loss of gross loss of appetite as one of its symptoms. At the end of the study, cyproheptadine hydrochloride intake daily amounted to a noticeable increase in weight than those who were on placebo.Another study by the National Center for Biotechnology Information found that cyproheptadine hydrochloride helped underweight people gain weight.

It is worth noting that people who are healthy or overweight can gain excess weight with the use of cyproheptadine hydrochloride. One study conducted in the Democratic Republic of Congo examined 499 people and concluded that out of the total participants, 73% of them overdosed on the substance and were at risk of obesity.

Is Apetamin Legal?

It is illegal to buy and sell Apetamin in the United States and other countries unless one has a valid and appropriate license. Those who use it, purchase from unverified websites and media platforms.Cyproheptadine appears to have some beneficial health uses, however, it must be prescribed by a doctor.

Additionally, cyproheptadine hydrochloride may lead to very serious health problems when misused including liver failure and coma. Unless prescribed by a medical professional, you should avoid cyproheptadine and its products.What’s more, this supplement is not regulated or approved by any food regulators including FDA. It may thus contain some ingredients contrary to what is listed on its label.

According to access data on the official website of the FDA, the importation and use of Apetamin and other products containing cyproheptadine hydrochloride are illegal and had been stopped.

Side Effects of Apetamin

Several studies have consistently found that cyproheptadine hydrochloride is well tolerated in the body and is safe for use. However, it is not approved by FDA. Apart from increased appetite, another common side effect of cyproheptadine hydrochloride is drowsiness. It has also been associated with hepatic toxicity. Other side effects of cyproheptadine hydrochloride may include shakiness or tremors, restlessness and irritability, sleepiness, blurred vision, nausea, diarrhea, rash, anemia, nasal dryness, migraines, headache, frequent urination, confusion, and low blood pressure.

Even if weight gain might seem positive, one should proceed with caution as it may result in excess weight gain and obesity. Published studies have also shown that cyproheptadine hydrochloride can interfere with the action of antihistamines, Parkinson’s disease drugs, and even antidepressants.


Apetamin is a supplement sold to people who want to gain weight. It is primarily made up of cyproheptadine hydrochloride, L-lysine, and vitamins. This supplement is not approved by FDA and therefore, its use in the U.S is illegal. Drowsiness, confusion, and liver toxicity are among its side effects.

Tatyana Dyachenko

For the past years, Tatyana has worked as a sex blogger and a relationship advisor. She has been featured in magazines such as Cosmopolitan, Teen Vogue. Vice, Tatler, Vanity Fair, and many others. Since 2016, Tatyana has focused on sexology, attended various training courses, participated in international conferences and congresses. “I wish people would address sexual issues in a timely manner! Forget shyness, prejudice and feel free to see a sex doctor for help or advice!” Tanya enjoys pursuing her flare for creativity through modelling, graffiti art, astronomy, and technology.