INGABE UFUTHA OLUHLANZEKILE WE-CBD UNAYO I-THC?

Imikhiqizo ye-CBD isazuza udumo, ngisho nangemva kokuxhunyaniswa nezingozi ezihlukahlukene. Ucwaningo oluningi olwenziwe ngemikhiqizo ye-CBD lukhombisa ukuthi inezinzuzo zezempilo kanye nempilo enhle. Imikhiqizo ye-CBD yenziwa ngesitshalo se-organic hemp esinezici zamakhemikhali ezahlukahlukene. Izakhi terpenes, flavonoid, cannabidiol (CBD), kanye tetrahydrocannabinol (THC). Ngokungafani nezinye izakhi, i-THC inemiphumela enobuthi, okungenzeka yenze abasebenzisi babe “phezulu.” Imikhiqizo ye-CBD yenziwa ngezinhlobo ezintathu; i-spectrum egcwele, i-spectrum ebanzi futhi ihlukanise. Kodwa-ke, ingabe i-CBD yodwa, eyaziwa nangokuthi i-CBD emsulwa iqukethe i-THC?

Ungayikhipha Kanjani I-Isolate noma I-CBD Emsulwa Ku-THC?

I-Cannabidiol (i-CBD) iyinhlanganisela etholakala esitshalweni se-cannabis. Ikhishwa kakhulu ezitshalweni ze-hemp ezitshalwe ngokwemvelo emazweni ase-USA njengeColorado, Kentucky, naseVermont. I-CBD ikhishwa kusetshenziswa izindlela ezahlukene ezifana ne-CO2 kanye ne-solvent yokukhiqiza i-CBD yezimboni. Ekukhishweni kwe-CO2, indlela ebaluleke kakhulu ithathwa njengengcono kakhulu. Ukukhishwa kwenzeka emakamelweni amathathu. I-CO2 ebaluleke kakhulu iphonswa ekamelweni eliqukethe izinto zezitshalo ze-hemp ezomile ezikhipha i-CBD engahluziwe ngoba ukungcola okufana nengcina namafutha kuyakhishwa. Ingxube iyashiswa ukuze iguqule i-CO2 ibe igesi. I-crude ifakwa kwi-distillation ukuze isuse ukungcola ngenxa yomehluko wamaphuzu abilayo.

Isizinda se-solvent sisebenzisa utshwala; I-butane ne-ethanol zivame ukusetshenziswa. I-ethanol iphonswa ekamelweni eliqukethe izinto zezitshalo ezomile ze-hemp ukuze kukhishwe i-CBD. Ngemuva kokukhipha, ingxube yotshwala ne-CBD iyashiswa ukuze kukhishwe utshwala. Umuntu angasebenzisa uwoyela we-olive njenge-solvent ukuze akhiphe i-CBD ekhaya. I-CBD ekhishwe ngokukhipha i-solvent ayidingi ukucutshungulwa okwengeziwe. Futhi, utshwala bukhipha i-chlorophyll ezintweni zezitshalo ezinikeza i-CBD ukunambitheka okubabayo. Kunezinhlobo ezintathu zezisekelo okumelwe zenziwe uwoyela CBD kusuka, i-CBD egcwele i-spectrum, i-CBD ebanzi, kanye ne-CBD yodwa. I-CBD egcwele i-spectrum inazo zonke izitshalo ze-hemp plant terpenes, okuhlanganisa ne-0.3% delta 9 THC, i-spectrum ebanzi inawo wonke ama-terpenes ngaphandle kwe-0.3% delta 9 THC. Ngemuva kokucutshungulwa, i-CBD iqhubeka nokucwengwa ukuze isuse wonke ama-terpenes neminonjana ye-0.3% delta 9 THC ukuze ihlukanise i-CBD. I-CBD eyedwa ixubene namafutha okuphatha njengamafutha e-MCT, uwoyela wekotapheya, uwoyela kakhukhunathi, noma uwoyela we-olive ukwenza uwoyela we-CBD omsulwa. Kwesinye isikhathi uwoyela we-CBD omsulwa ungaba nowoyela othwala ongaphezu kweyodwa.

Ingabe Amafutha E-CBD Ahlanzekile Akwenza Uphakeme?

I-CBD ikhishwa esitshalweni se-hemp ngokwemvelo enenani eliphansi kakhulu le-delta 9 THC; lokhu kuyinhlanganisela esitshalweni se-cannabis eyenza umuzwa ophezulu. Ivamise ukutholakala kunsangu. Ukuthatha uwoyela we-Pure CBD ngeke kukunike umphumela ophezulu ngenxa yenani eliphansi le-delta 9 THC. I-CBD eyodwa iye yacwengwa ngemva kokucutshungulwa ukuze ikhululeke kunoma yikuphi ukungcola.

Ukusetshenziswa Kwamafutha e-CBD ahlanzekile

Amafutha e-CBD ahlanzekile akhulula ubuhlungu nokuvuvukala kwezempilo kanye nokuphila kahle jikelele. I-CBD ithinta ama-ECS receptors afana ne-CB1 ngokunciphisa ukuwohloka kwama-transmitters kanye nokunciphisa isivinini samasignali ezinzwa adluliselwa phakathi kwamaseli ezinzwa. Uwoyela we-CBD ungasetshenziswa kuzo zonke izinhlobo zobuhlungu, kufaka phakathi imizwa nobuhlungu beqolo.

U-Lee, u-Jonathan LC, et al (2017) iphakamisa ukuthi i-CBD ithinta amazinga e-serotonin. I-Serotonin iyi-neurotransmitter enesibopho semisebenzi yomzimba efana nemizwa noma isifiso sokudla. I-serotonin ephezulu ibangela isimo sengqondo esihle, ngaleyo ndlela ukukhathazeka okuphansi noma ukucindezeleka. Ucwaningo luphinde lubonise ukuthi i-CBD isebenza njenge-antidepressant, ebuye ilawule amazinga e-serotonin. Abantu abanezimpawu zokuhoxa njengokukhathazeka bangazuza kuwoyela we-CBD ngoba lezi zimpawu zivela ku-serotonin ephansi.

Imiphumela Engenzeka Engenzeka Yamafutha e-CBD Nge-THC

Noma i-CBD ingenayo imiphumela emibi ebulalayo, isenayo eminye imiphumela emincane njengokucanuzela kwenhliziyo, okubangela ukuhlanza. Lokhu kungabangelwa uwoyela we-CBD omningi noma ukuzwela uwoyela we-CBD. Kodwa-ke, kungagwenywa ukusebenzisa amanani amancane kawoyela we-CBD kuqala, bese ukhuphula umthamo kamuva lapho ukhululekile ngokuphelele ngamafutha e-CBD. Umlomo owomile noma i-cottonmouth omunye umphumela ongaseceleni ongase ube ngenxa yobuchopho obuthumela izimpawu zemizwa ku-epithelial ukuze kukhiqizwe amathe amancane. I-CBD yenza kusebenze i-CB1 ne-CB2 futhi ivimbe ukukhishwa kwamathe emlonyeni. Lokhu kungavuselelwa ngokuhlala ungenawo amanzi. Uwoyela we-CBD oxutshwe ne-melatonin uyasiza ekulaleni. Nokho, kungase kubangele ukozela okungafunwa, ikakhulukazi phakathi nosuku lapho wenza umsebenzi ohehayo njengokushayela.

Ungawathatha Kanjani Amafutha e-CBD ahlanzekile

Kunezindlela ezine zokuthatha uwoyela we-CBD. Okokuqala, yengeze esidlweni sakho ozithandayo noma esiphuzweni, okukusiza ukuthi ugweme ukunambitheka okubi kwe-CBD. Futhi, ungayisebenzisa ngokungemthetho ngokufaka amaconsi ambalwa ngaphansi kolimi lwakho bese uyibamba imizuzwana engama-60 ngaphambi kokugwinya. Ngaphandle kwalokho, ungayisebenzisa ngokwezihloko ngokuyixuba emikhiqizweni yezihloko noma ukuyifaka ngqo esikhumbeni sakho. Okokugcina, ukhetha ukuyisebenzisa ekubhakeni.

Isiphetho

Amafutha e-CBD ahlanzekile enziwe nge-CBD ecwengisiswe kakhulu, okusho ukuthi ayinakho ukungcola, okuhlanganisa i-0.3% Delta 9 THC enikeza umphumela ophezulu. Ngakho-ke uma ufuna ukusebenzisa uwoyela we-CBD, ungaya kuwoyela we-Pure CBD ngoba ngeke ukhathazeke ngokuhluleka ukuhlolwa kwezidakamizwa. Kodwa-ke, kungase kungabi isiqinisekiso sokuthi uzogwema ukuthatha i-THC ngokuphelele ngenkathi usebenzisa imikhiqizo engabodwa. I-THC, okuyisici sesibili esibusa kakhulu esitshalweni se-hemp, kungase kube nzima ukuyikhipha ngokugcwele, noma kusetshenziswa i-CO2.

Okubhekwayo

U-Lee, JL, Bertoglio, LJ, Guimarães, FS, & Stevenson, CW (2017). Ukulawulwa kwe-Cannabidiol kwemizwa nokucubungula inkumbulo yomzwelo: ukubaluleka kokwelapha izinkinga ezihlobene nokukhathazeka nokusebenzisa kabi izidakamizwa. Iphephabhuku laseBrithani le-pharmacology, i-174 (19), 3242-3256.