INGABE UFUTHA OLUHLANZEKILE WE-CBD UNAYO I-THC?

INGABE UFUTHA OLUHLANZEKILE WE-CBD UNAYO I-THC?

Imikhiqizo ye-CBD isazuza udumo, ngisho nangemva kokuxhunyaniswa nezingozi ezihlukahlukene. Ucwaningo oluningi olwenziwe ngemikhiqizo ye-CBD lukhombisa ukuthi inezinzuzo zezempilo kanye nempilo enhle. Imikhiqizo ye-CBD yenziwa ngesitshalo se-organic hemp esinezici zamakhemikhali ezahlukahlukene. Izakhi terpenes, flavonoid, cannabidiol (CBD), kanye tetrahydrocannabinol (THC). Ngokungafani nezinye izakhi, i-THC inemiphumela enobuthi, okungenzeka yenze abasebenzisi babe “phezulu.” Imikhiqizo ye-CBD yenziwa ngezinhlobo ezintathu; i-spectrum egcwele, i-spectrum ebanzi futhi ihlukanise. Kodwa-ke, ingabe i-CBD yodwa, eyaziwa nangokuthi i-CBD emsulwa iqukethe i-THC?

Ungayikhipha Kanjani I-Isolate noma I-CBD Emsulwa Ku-THC?

I-Cannabidiol (i-CBD) iyinhlanganisela etholakala esitshalweni se-cannabis. Ikhishwa kakhulu ezitshalweni ze-hemp ezitshalwe ngokwemvelo emazweni ase-USA njengeColorado, Kentucky, naseVermont. I-CBD ikhishwa kusetshenziswa izindlela ezahlukene ezifana ne-CO2 kanye ne-solvent yokukhiqiza i-CBD yezimboni. Ekukhishweni kwe-CO2, indlela ebaluleke kakhulu ithathwa njengengcono kakhulu. Ukukhishwa kwenzeka emakamelweni amathathu. I-CO2 ebaluleke kakhulu iphonswa ekamelweni eliqukethe izinto zezitshalo ze-hemp ezomile ezikhipha i-CBD engahluziwe ngoba ukungcola okufana nengcina namafutha kuyakhishwa. Ingxube iyashiswa ukuze iguqule i-CO2 ibe igesi. I-crude ifakwa kwi-distillation ukuze isuse ukungcola ngenxa yomehluko wamaphuzu abilayo.

Isizinda se-solvent sisebenzisa utshwala; I-butane ne-ethanol zivame ukusetshenziswa. I-ethanol iphonswa ekamelweni eliqukethe izinto zezitshalo ezomile ze-hemp ukuze kukhishwe i-CBD. Ngemuva kokukhipha, ingxube yotshwala ne-CBD iyashiswa ukuze kukhishwe utshwala. Umuntu angasebenzisa uwoyela we-olive njenge-solvent ukuze akhiphe i-CBD ekhaya. I-CBD ekhishwe ngokukhipha i-solvent ayidingi ukucutshungulwa okwengeziwe. Futhi, utshwala bukhipha i-chlorophyll ezintweni zezitshalo ezinikeza i-CBD ukunambitheka okubabayo. Kunezinhlobo ezintathu zezisekelo okumelwe zenziwe uwoyela CBD kusuka, i-CBD egcwele i-spectrum, i-CBD ebanzi, kanye ne-CBD yodwa. I-CBD egcwele i-spectrum inazo zonke izitshalo ze-hemp plant terpenes, okuhlanganisa ne-0.3% delta 9 THC, i-spectrum ebanzi inawo wonke ama-terpenes ngaphandle kwe-0.3% delta 9 THC. Ngemuva kokucutshungulwa, i-CBD iqhubeka nokucwengwa ukuze isuse wonke ama-terpenes neminonjana ye-0.3% delta 9 THC ukuze ihlukanise i-CBD. I-CBD eyedwa ixubene namafutha okuphatha njengamafutha e-MCT, uwoyela wekotapheya, uwoyela kakhukhunathi, noma uwoyela we-olive ukwenza uwoyela we-CBD omsulwa. Kwesinye isikhathi uwoyela we-CBD omsulwa ungaba nowoyela othwala ongaphezu kweyodwa.

Ingabe Amafutha E-CBD Ahlanzekile Akwenza Uphakeme?

I-CBD ikhishwa esitshalweni se-hemp ngokwemvelo enenani eliphansi kakhulu le-delta 9 THC; lokhu kuyinhlanganisela esitshalweni se-cannabis eyenza umuzwa ophezulu. Ivamise ukutholakala kunsangu. Ukuthatha uwoyela we-Pure CBD ngeke kukunike umphumela ophezulu ngenxa yenani eliphansi le-delta 9 THC. I-CBD eyodwa iye yacwengwa ngemva kokucutshungulwa ukuze ikhululeke kunoma yikuphi ukungcola.

Ukusetshenziswa Kwamafutha e-CBD ahlanzekile

Amafutha e-CBD ahlanzekile akhulula ubuhlungu nokuvuvukala kwezempilo kanye nokuphila kahle jikelele. I-CBD ithinta ama-ECS receptors afana ne-CB1 ngokunciphisa ukuwohloka kwama-transmitters kanye nokunciphisa isivinini samasignali ezinzwa adluliselwa phakathi kwamaseli ezinzwa. Uwoyela we-CBD ungasetshenziswa kuzo zonke izinhlobo zobuhlungu, kufaka phakathi imizwa nobuhlungu beqolo.

U-Lee, u-Jonathan LC, et al (2017) iphakamisa ukuthi i-CBD ithinta amazinga e-serotonin. I-Serotonin iyi-neurotransmitter enesibopho semisebenzi yomzimba efana nemizwa noma isifiso sokudla. I-serotonin ephezulu ibangela isimo sengqondo esihle, ngaleyo ndlela ukukhathazeka okuphansi noma ukucindezeleka. Ucwaningo luphinde lubonise ukuthi i-CBD isebenza njenge-antidepressant, ebuye ilawule amazinga e-serotonin. Abantu abanezimpawu zokuhoxa njengokukhathazeka bangazuza kuwoyela we-CBD ngoba lezi zimpawu zivela ku-serotonin ephansi. 

Imiphumela Engenzeka Engenzeka Yamafutha e-CBD Nge-THC

Noma i-CBD ingenayo imiphumela emibi ebulalayo, isenayo eminye imiphumela emincane njengokucanuzela kwenhliziyo, okubangela ukuhlanza. Lokhu kungabangelwa uwoyela we-CBD omningi noma ukuzwela uwoyela we-CBD. Kodwa-ke, kungagwenywa ukusebenzisa amanani amancane kawoyela we-CBD kuqala, bese ukhuphula umthamo kamuva lapho ukhululekile ngokuphelele ngamafutha e-CBD. Umlomo owomile noma i-cottonmouth omunye umphumela ongaseceleni ongase ube ngenxa yobuchopho obuthumela izimpawu zemizwa ku-epithelial ukuze kukhiqizwe amathe amancane. I-CBD yenza kusebenze i-CB1 ne-CB2 futhi ivimbe ukukhishwa kwamathe emlonyeni. Lokhu kungavuselelwa ngokuhlala ungenawo amanzi. Uwoyela we-CBD oxutshwe ne-melatonin uyasiza ekulaleni. Nokho, kungase kubangele ukozela okungafunwa, ikakhulukazi phakathi nosuku lapho wenza umsebenzi ohehayo njengokushayela.

Ungawathatha Kanjani Amafutha e-CBD ahlanzekile

Kunezindlela ezine zokuthatha uwoyela we-CBD. Okokuqala, yengeze esidlweni sakho ozithandayo noma esiphuzweni, okukusiza ukuthi ugweme ukunambitheka okubi kwe-CBD. Futhi, ungayisebenzisa ngokungemthetho ngokufaka amaconsi ambalwa ngaphansi kolimi lwakho bese uyibamba imizuzwana engama-60 ngaphambi kokugwinya. Ngaphandle kwalokho, ungayisebenzisa ngokwezihloko ngokuyixuba emikhiqizweni yezihloko noma ukuyifaka ngqo esikhumbeni sakho. Okokugcina, ukhetha ukuyisebenzisa ekubhakeni.

Isiphetho

Amafutha e-CBD ahlanzekile enziwe nge-CBD ecwengisiswe kakhulu, okusho ukuthi ayinakho ukungcola, okuhlanganisa i-0.3% Delta 9 THC enikeza umphumela ophezulu. Ngakho-ke uma ufuna ukusebenzisa uwoyela we-CBD, ungaya kuwoyela we-Pure CBD ngoba ngeke ukhathazeke ngokuhluleka ukuhlolwa kwezidakamizwa. Kodwa-ke, kungase kungabi isiqinisekiso sokuthi uzogwema ukuthatha i-THC ngokuphelele ngenkathi usebenzisa imikhiqizo engabodwa. I-THC, okuyisici sesibili esibusa kakhulu esitshalweni se-hemp, kungase kube nzima ukuyikhipha ngokugcwele, noma kusetshenziswa i-CO2.

Okubhekwayo

U-Lee, JL, Bertoglio, LJ, Guimarães, FS, & Stevenson, CW (2017). Ukulawulwa kwe-Cannabidiol kwemizwa nokucubungula inkumbulo yomzwelo: ukubaluleka kokwelapha izinkinga ezihlobene nokukhathazeka nokusebenzisa kabi izidakamizwa. Iphephabhuku laseBrithani le-pharmacology, i-174 (19), 3242-3256.

U-Anastasia Filipenko ungudokotela wezengqondo wezempilo nokuphila kahle, udokotela wesikhumba kanye nombhali ozisebenzelayo. Uvamise ukuhlanganisa ubuhle nokunakekelwa kwesikhumba, izitayela zokudla nokudla, ezempilo nokuqina kanye nobudlelwano. Uma engazami imikhiqizo emisha yokunakekelwa kwesikhumba, uzomthola ethatha ikilasi lokuhamba ngebhayisikili, enza i-yoga, efunda epaki, noma ezama iresiphi entsha.

Okwakamuva okuvela ku-CBD