INGABE UFUTHA WE-CBD UKUNIKA AMANDLA?

INGABE UFUTHA WE-CBD UKUNIKA AMANDLA?

Abantu abaningi bafaka uwoyela we-CBD endleleni yabo yokuphila ngezizathu ezahlukene. Abakhiqizi bezikhangiso zabathengi bathi le cannabinoid ingakwazi ukulawula izimo ezinjengobuhlungu, ukudangala, ukukhathazeka, izifo, ukugxila, inkumbulo, ukuqonda kanye nokululama. Njengamanje, abukho ubufakazi besayensi obanele bokukweleta uwoyela we-CBD wamandla nezinzuzo ezihlobene. Nokho, ezinye izifundo zisikisela lokho uwoyela CBD ithuthukisa ezinye izici ezikhulisa amandla ngokungaqondile, njengoba kuqokonyiswe kulesi sihloko. Uwoyela we-CBD awunconyelwe ukwelapha noma ukwelapha izinkinga ezihlobene namandla, ikakhulukazi ngoba i-FDA ayizange iyivume i-cannabinoid.

Ukuqonda Amafutha e-CBD

I-CBD ingenye yezinhlanganisela eziningi ezisebenzayo ezitshalweni ze-cannabis. Nakuba uwoyela we-CBD ungakhishwa ezitshalweni zensangu noma ze-hemp, uMthethosivivinywa wePulazi uthatha uwoyela we-CBD we-hemp ongaphansi kuka-0.3% osemthethweni we-THC. Iningi lemikhiqizo lisebenzisa i-hemp ukwenza imikhiqizo yalo kawoyela we-CBD ngoba insangu ine-TCH ephezulu.

Imikhiqizo kawoyela ye-CBD ihlanganisa izinhlaka, iminti, amaphilisi, ama-softgels, ama-tinctures, ama-vapes, ama-hemp buds agoqwe ngaphambili, ama-topical, nezinto ezifuywayo. Ngaphandle kwalokho, kunezindlela ezintathu ezahlukene zikawoyela we-CBD ezichazwe ngokwakhiwa ngale ndlela elandelayo;

Amafutha e-CBD agcwele i-spectrum

Iqukethe ama-terpenes, ama-flavonoid, nama-cannabinoids amaningi njenge-CBD, i-CBT, i-CBN, i-CBG, kanye ne-psychoactive THC, exhunywe nomthelela ogcwele wokugqugquzela.

I-Broad-spectrum CBD Amafutha

Lokhu kwakhiwa kufana nowoyela we-CBD ophelele ekwakhiweni, kuphela ukuthi ayinayo i-psychoactive THC.

Uwoyela we-CBD osuselwe yedwa

 Lawa mafutha e-CBD awanawo ama-terpenes, ama-flavonoid, nama-cannabinoids. Iqukethe kuphela i-CBD futhi ithathwa njengokubunjwa okumsulwa.

Iningi lezimfundamakhwela kanye nabantu abathola ukunambitheka komhlaba kawoyela we-CBD okungabekezeleleki bagxila kuzodwa ngoba azinambitheki futhi azinaphunga. Kodwa-ke, amafutha e-CBD agcwele futhi ane-spectrum ebanzi ayisinqumo sabantu abaningi ngomphumela wabo ophelele wokugqugquzela, futhi lokhu kwakamuva kuhle uma ufuna ukugwema i-psychoactive THC ngomphumela wayo 'owenziwe ngamatshe' noma 'ophezulu'.

Ingabe Amafutha e-CBD Angakunika Amandla?

Umuntu angase aswele amandla ngenxa yezizathu eziningi, okuhlanganisa izimo ezingapheli nobuhlungu, ukudla, ukungalali ngokwanele, ukozela emini, nokucindezeleka. Ucwaningo olwenziwe ngu I-Moltke & Hindocha, (2021) iphakamisa ukuthi uwoyela we-CBD ungaphatha lezi zimo futhi usize umuntu aphinde athole amandla. Noma kunjalo, abukho ubufakazi obanele bokufakazela ukuthi uwoyela we-CBD uyawathinta amandla.

I-CBD Amafutha Isebenzisana ne-Endocannabinoid System

Okuningi akwaziwa ngowoyela we-CBD, okuhlanganisa nokuthi usebenza kanjani. Kodwa-ke, umzimba womuntu unohlelo lwe-endocannabinoid (ECS) olunama-enzyme, ama-cannabinoids, nama-receptors (CB1 kanye ne-CB2) alawula ukusebenza kwawo wonke umzimba futhi angasiza ngamandla. I-ECS ithonya imisebenzi nezinqubo ezibalulekile emzimbeni, okuhlanganisa ukubona, ubuhlungu, ukugaya, ukungatheleleki, ukulala, izimiso zokushisa, nokusutha. Ngokuvumelana ne U-Di Marzo no-Piscitelli, (2015), uhlelo lwe-endocannabinoid lusebenzisana nama-cannabinoids, futhi lapho umuntu ethatha uwoyela we-CBD, ama-cannabinoids abopha kuma-receptors. Lokhu kubeka ama-receptors endleleni yokulungisa, ezama ukubuyisela yonke into ekulinganeni. Kanjalo, ukusebenzisana kukawoyela we-ECS-CBD kunganikeza umzimba amandla. Kodwa-ke, kunesidingo sezifundo ezengeziwe ezivumbulula ubukhona besistimu enjalo kanye nemiphumela yayo emandleni.

Amafutha e-CBD Wokuphathwa Kwezinhlungu

Ubuhlungu buphakathi kwezici eziningi eziqeda amandla. Ngakho-ke, noma yini enganciphisa ubuhlungu ingase ibangele ukuzuza amandla. Kunezifundo ezilinganiselwe ze-CBD ekulawuleni ubuhlungu. Nokho, isifundo esisodwa by U-Vučković, uSrebro, noVujović et al. (2018) Ukuhlaziya izifundo ze-CBD kusukela ngo-1975 kuya ku-2018 kwaphetha ngokuthi uwoyela we-CBD ungasiza ngezinhlobo ezahlukene zobuhlungu, kuhlanganise ne-neuropathic, umdlavuza, kanye nezinhlungu ze-fibromyalgia. Ucwaningo luphakamisa ukuthi i-CBD ikhulula ubuhlungu obungapheli, okunomthelela ekuzuzeni amandla. Noma kunjalo, ukubuyekezwa akubonisi ukuthi uwoyela we-CBD unganika umuntu amandla.

Amafutha e-CBD Wokulala Okuthuthukisiwe

Ukulala kuyilungiselelo elivumela umzimba ukuba uphumule futhi ulungiselele ukubuyela ezinzwaneni lapho uvuka. Abantu abanokuqwasha kanye nekhwalithi yokulala engeyinhle ngokuvamile bazizwa bekhathele njengoba benganikeli uhlelo isikhathi esanele sokuvuselela. Ingabe uwoyela we-CBD ungathuthukisa ukulala komuntu futhi umnike amandla? Ucwaningo olulodwa ngo Shannon, Lewis, & Lee et al. (2019) ngezifundo ezingama-72 kuphawulwe ukuthi amaphilisi kawoyela we-CBD angama-25 mg asize i-66.9% yabahlanganyeli ukuthi bathole ukulala okungcono, kuyilapho ama-79.2% abika ukukhathazeka okuncishisiwe. Ucwaningo luphakamisa ukuthi uwoyela we-CBD ungakhulisa ubuthongo bomuntu futhi unciphise ukukhathazeka, umnikeze amandla ngokweqiniso. Kodwa-ke, lolu cwaningo lwalubandakanya inani elincane labantu elingakwazi ukwenza ukuqagela okunembile kwesayensi.

Ingabe Kufanele Uthathe Amafutha E-CBD Ukuze Uthole Amandla?

Izifundo zamanje azinikezi ubufakazi obanele bokuqinisekisa ngokwesayensi ukuthi uwoyela we-CBD ungasiza ngokushoda kwamandla. Futhi, i-FDA ayizange ivume uwoyela we-CBD wamandla, okusho ukuthi awukho umthamo onconywayo kawoyela we-CBD. Izikhala eziningi zolwazi zizungeza izifundo ze-CBD, futhi kunenqwaba yolwazi mayelana nowoyela we-CBD ongaziwa. Konke lokhu kukhombisa ukuthi ukuthatha uwoyela we-CBD nganoma yisiphi isizathu kuyindlela eyingozi.

Isiphetho

Abukho ubufakazi obanele bokukweleta uwoyela we-CBD ngokunikeza umuntu amandla. Nakuba ucwaningo lokuqala lubonisa ukuthi uwoyela we-CBD unganciphisa ukukhathazeka nobuhlungu futhi ube ngcono ukulala komuntu, akwaziwa ukuthi lokhu kungenzeka kangakanani nokuthi le miphumela iholela ekuzuzeni amandla. Uma uhlanganisa uwoyela we-CBD endleleni yakho yokuphila, kufanele uthintane nodokotela kusengaphambili.

Okubhekwayo

Moltke, J., & Hindocha, C. (2021). Izizathu Zokusebenzisa I-Cannabidiol: Ucwaningo Lwesigaba Esiphambene Sabasebenzisi Be-CBD, Okugxile Ekucindezelekeni Okuzibonayo, Ukukhathazeka, Nezinkinga Zokulala. Ijenali Yocwaningo LweCannabis, 3(1), i-1-12.

Di Marzo, V., & Piscitelli,

F. (2015). Uhlelo lwe-Endocannabinoid kanye nokuguqulwa kwalo ngama-Phytocannabinoids. Neurotherapeutics, 12(4), i-692-698.

Vučković, S., Srebro, D., Vujović,

KS, Vučetić, Č., & Prostran, M. (2018). Ama-Cannabinoids Nobuhlungu: Okusha

Imibono Evela Kuma-Old Molecules. I-Frontiers In Pharmacology, 1259.

Shannon, S., Lewis, N., Lee,

H., & Hughes, S. (2019). I-Cannabidiol Ekukhathazekeni Nokulala: Icala Elikhulu

Uchungechunge. I-Permanente Journal,23.

I-Nutritionist, Cornell University, MS

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Okwakamuva okuvela ku-CBD