INGABE I-VAPING CBD IZOVELA EKUHLOLWENI KWEZIDAMI?

INGABE I-VAPING CBD IZOVELA EKUHLOLWENI KWEZIDAMI?

Ingabe ubulokhu ufutha futhi ukhathazekile ngokuthi kutholwa ukuhlolwa kwezidakamizwa? Ungabi novalo. Le ndatshana ichaza kabanzi mayelana ne-vaping CBD kanye nokuthandwa kwezidakamizwa nokuthi lezi zinto zombili zihlobene kanjani.

Ukuhlolwa kwezidakamizwa kuvame ukuhlola ubukhona be-THC noma ama-metabolite ahlobene. Lokho kusho ukuthi uma ufaka i-CBD ngemikhondo ye-THC kuyo, kungenzeka wehluleke ukuhlolwa kwezidakamizwa. Ukuba khona kwe-THC noma ama-metabolites ayo kukwenza wehluleke ekuhlolweni kwezidakamizwa. Ngakho-ke, ukuthi uzophumelela yini ekuhlolweni kwezidakamizwa kuncike kuhlobo lwe-CBD olisebenzisayo. Yonke imikhiqizo ye-CBD etholakala ku-hemp yezimboni isemthethweni futhi ihlala inamaphesenti aphansi kuya kwayiwa e-THC. Nakuba eminye imikhiqizo inamaphesenti angaphansi kwe-0.3 noma ayikho i-THC, izingozi zenzeka ngesikhathi sokucubungula; ngakho-ke kungase kungabi njalo. Ngaphezu kwalokho, abanye abakhiqizi bangase babhale kabi umkhiqizo, bakudukise. Qhubeka ufunde ukuthola ukuthi i-vaping CBD izovela yini ekuhlolweni kwakho kwezidakamizwa.

ISINGENISO KU-CBD

I-CBD ingenye yezinhlanganisela eziyinhloko ezivunwa kuCannabis Sativa. I-Cannabis isitshalo esisebenza ngezindlela eziningi esilinyelwa izinhloso eziningi, njengembewu ye-hemp yokudla, ukusetshenziswa kokuzijabulisa, izinzuzo zokwelapha, nezinto zokwakha. Ngokuvumelana ne ucwaningo, i-cannabis iqukethe ngaphezu kwe-400 organic chemical compounds, okuyi-80 yayo esebenza ngokuphila. Izithako eziyinhloko ze-bioactive ku-cannabis zingama-cannabinoids njenge-CBD ne-THC. Lawa ma-cannabinoids ahlukile ku-cannabis, futhi asikho esinye isitshalo esiwaqukethe. Amanye ama-cannabinoids amaningi ngaphandle kwe-THC ne-CBD yi-cannabinol (CBN), i-cannabigerol (CBG), kanye ne-Cannabichromene (CBC).

I-THC iyisithako esiyinhloko se-bioactive ku-cannabis. Isebenza ngokwengqondo futhi iyadakisa yingakho iletha imiphumela ejabulisayo neluthayo, ngokulandelana. Kodwa-ke, i-CBD ayinawo umphumela onjalo. Campos et al. (2012) ibonise izinzuzo zokwelapha ze-CBD ekwelapheni ukukhathazeka nokudangala. Ngokusho kokuphathwa kokudla nezidakamizwa, inhlanganisela ye-CBD equkethe ngaphezu kwamaphesenti angu-0.3 iTHC ayikho emthethweni. Ihlelelwe njengomuthi weSheduli I ngu Isikhungo Sokuqinisa Izidakamizwa wase-United States of America. Uma uthatha iTHC, inamathela kuma-receptors amaningi ebuchosheni, ilethe imiphumela ehlukene. Izindawo eziyinhloko lapho i-CBD ibopha khona ebuchosheni kanye nemiphumela ebuhlungu.

Indawo yobuchophoEffects
HippocampusIkhubaza amakhono engqondo esikhashana njengenkumbulo
I-NeocortexIphazamisa ukwahlulela komsebenzisi kanye nomuzwa wenjabulo
I-Basal gangliaKuthinta isikhathi sokusabela nokunyakaza
hypothalamusYandisa isifiso sokudla isiyonke
I-nucleus accumbentIdala imiphumela yenjabulo
U-AmygdalaLokhu kuholela ekwethukeni nasekuphazamisekeni kwengqondo
cerebellumUmsebenzisi uzizwa edakiwe
UbuchophoYehlisa isicanucanu nokuhlanza
UmgogodlaYehlisa izinhlungu

Uma uthatha i-CBD, ayibophi ama-receptors afanayo ebuchosheni njenge-THC. Ngakho-ke, ososayensi abakaqiniseki ukuthi le nhlanganisela ihlangana kanjani nomzimba ukuze isebenze imiphumelaI-Yarar (2021) uthe i-CBD ibophezela kuma-endocannabinoid receptors, okwenza kube nokulinganisela. Devinsky et al. (2014) uthole izinzuzo ezilandelayo ezingaba khona ze-CBD:

  • Kwehlisa ukuvuvukala
  • Ilawula ukuphazamiseka kwengqondo njengokukhathazeka
  • Isidambisi sobuhlungu obungapheli
  • Ivimbela ukuhlanza kanye nemiphumela ehlobene
  • Ilawula ukusebenza kwengqondo
  • Ikhuthaza i-neuroprotection

KUSEBENZA KANJANI UKUHLOLA UDAKATHI WE-CanNABIS?

Uma umuntu ehlolwa umchamo, kuqondiswe lezi zinto ezilandelayo:

  • Utshwala
  • Amphetamine
  • Benzodiazepines
  • Ama-opiates
  • cocaine
  • insangu

Ngakho-ke, ukuhlolwa komchamo kungenye yezivivinyo eziyinhloko ze-cannabis. Ukuhlolwa komchamo kusebenza njengokuhlolwa kwe-immunoassay kusetshenziswa amasosha omzimba ukuze azinamathisele emithini ethile nama-metabolites. Lawa ma-antibodies aqondise i-THC kanye nama-metabolites ayo ekuhlolweni kwezidakamizwa ze-cannabis. Isignali evumayo izovezwa lapho amasosha omzimba ebopha into eqondiwe, okusho ukuthi awukaphumelelanga ekuhlolweni kwesidakamizwa.

Ngokuvumelana ne I-Kulak & Griswold (2019), uHulumeni wase-United States ubeka amanani athile okugxilisa ingqondo phakathi nokuhlolwa kwezidakamizwa. Kodwa-ke, uma ukuhlolwa kubuyisela inani lokuhlushwa ngaphansi kwalelo elidingwa uhulumeni wobumbano, ukuhlolwa kwesidakamizwa kubonisa ukuthi awunayo, futhi uzobe usuphumelele. Nakuba ukugxila kwezinto ezingafuneki emzimbeni wakho kungaphezu kokugxilisa okudingekayo, amadivaysi abuyisela imiphumela emihle; ngakho-ke uzobe uhlulekile ukuhlolwa kwezidakamizwa. Umphumela oqondile awuchazi ukuthi uhlulekile ukuhlolwa kwezidakamizwa, njengoba ungase wenze ezinye izivivinyo zokulandelela ukuze uqinisekiswe.

Uzohlolwa okuqinisekisayo okufana ne-mass spectroscopy, i-gas chromatography, kanye ne-high-performance liquid chromatography. Izindlela ezinembile zokuthola izidakamizwa ezingafuneki nama-metabolites emzimbeni zikhona. Lapho ehlola imiphumela emihle, umhlinzeki wokunakekelwa kwezempilo kufanele aqaphele njengoba kungenzeka ukuthi athole imiphumela engemihle noma engelona iqiniso. Abantu abathola ukuthi banalo ngesikhathi behlolwa umchamo bayakhuthazwa ukuthi bakhulume nodokotela babo babone indlela eya phambili.

Ukuhlolwa kwezidakamizwa ze-cannabis kungaba kuhle uma usebenzise i-CBD egcwele ngemuva kwezinsuku ezintathu. Kungase futhi kubonakale uma usebenzisa insangu kanzima izinsuku ezingamashumi amathathu. Ukuhlolwa kwezidakamizwa ezinhle kwenzeka ngenxa yokuba khona kwe-THC. Kuyinhlanganisela encibilikayo ngamafutha, futhi umzimba uwugcina ezingxenyeni zawo zamafutha. Lapho umuntu enza i-metabolism ukuze ashise lawa mafutha, i-THC ikhululwa kancane futhi ikhishwe yizinso njengama-metabolites. Abacwaningi bahlola umoya noma amathe lapho kungenankinga ukuba selabhorethri. Nokho, le ndlela iseyintsha, ayithuthukisiwe, futhi ayikasetshenziswa njalo.

INGABE UNGAHLULEKA UKUHLOLA IMITHI KUSUKA EVAPING CBD?

Akunakwenzeka ukuhluleka ukuhlolwa kwezidakamizwa kusuka ku-vaping CBD equkethe ngaphansi kwamaphesenti angu-0.3 we-THC. Imikhiqizo ye-CBD efana ne-CBD egcwele-spectrum inezinga elithile le-THC. Uma inani le-THC emkhiqizweni we-CBD lidlula amaphesenti angu-0.3, ungase uhluleke ukuhlolwa kwezidakamizwa.

Njengoba i-CBD ingumkhiqizo ongavinjelwe, abakhiqizi abathile abahloniphekile. Imikhiqizo yabo ingase ibe ne-THC, kodwa basho okuhlukile kulebula yabo, bayakudukisa. Qinisekisa ukuthi uthenga wonke umkhiqizo wakho we-CBD ezinkampanini ezihlonishwayo futhi ungaphansi kwezindawo zokucwaninga zezinkampani zangaphandle ukuze zihlolwe.

UMUGQA WOKUPHAKATHI

Ukuhlolwa kwezidakamizwa kuvame ukuhlola ubukhona be-THC noma ama-metabolite ahlobene. Lokho kusho ukuthi uma ufaka i-CBD ngemikhondo ye-THC kuyo, kungenzeka wehluleke ukuhlolwa kwezidakamizwa. I-THC iyisithako esiyinhloko se-bioactive esitholakala ku-cannabis. Isebenza ngokwengqondo futhi iyadakisa yingakho iletha imiphumela ejabulisayo neluthayo, ngokulandelana. Kodwa-ke, i-CBD ayinawo umphumela onjalo odonse ososayensi ukuthi bafunde izinzuzo zayo zokwelapha ekwelapheni ukukhathazeka nokudangala. Ngokusho kokuphathwa kokudla nezidakamizwa, inhlanganisela ye-CBD equkethe ngaphezu kwamaphesenti angu-0.3 iTHC ayikho emthethweni. Ihlelelwe njengeSithako Sohlelo I yi-Drug Enforcement Agency yase-United States of America. Uma uthatha i-THC, inamathela kuma-receptors amaningi ebuchosheni, ngaleyo ndlela ilethe imiphumela ehlukile.

IZINDAWO ZOLWAZI

Campos, AC, Moreira, FA, Gomes, FV, Del Bel, EA, & Guimaraes, FS (2012). Izindlela Eziningi Ezihilelekile Emandleni Emithi Enkulu-Spectrum Ye-Cannabidiol Ezinkinga Zengqondo. Ukuhwebelana Kwefilosofi Yenhlangano Yasebukhosini B: Isayensi Yezinto Eziphilayo, 367(1607), 3364-3378.

Devinsky, O., Cilio, MR, Cross, H., Fernandez-Ruiz, J., French, J., Hill, C., … & Friedman, D. (2014). I-Cannabidiol: I-Pharmacology kanye Nendima Engaba Khona Yokwelapha Esithuthwaneni Nezinye Izifo Ze-Neuropsychiatric. I-Epilepsia, 55(6), 791-802.

I-Kulak, JA, & Griswold, KS (2019). Ukusetshenziswa Kwezidakamizwa Nezintsha Ezintsha: Ukuqashelwa Nokuphathwa. Udokotela Womndeni waseMelika, 99(11), 689-696.

U-Yarar, E. (2021). Iqhaza Nomsebenzi Wohlelo Lwe-Endocannabinoid Kuzifo Ezinkulu Zokucindezeleka. I-Cannabis Yezokwelapha Kanye nama-Cannabinoids, 4(1), 1-12.

I-Nutritionist, Cornell University, MS

Ngikholwa ukuthi isayensi yezokudla iwumsizi omuhle kakhulu wokuthuthukisa impilo nokwelashwa okungeziwe ekwelashweni. Umgomo wami uwukusiza abantu ukuba bathuthukise impilo yabo nokuphila kahle ngaphandle kokuzihlukumeza ngemikhawulo yokudla engadingekile. Ngingumsekeli wempilo enempilo - ngidlala ezemidlalo, ngibhayisikili, futhi ngibhukuda echibini unyaka wonke. Ngomsebenzi wami, ngivezwe kuVice, Country Living, Harrods magazine, Daily Telegraph, Grazia, Women's Health, kanye neminye imithombo yezindaba.

Okwakamuva okuvela ku-CBD