INGABE UZIZWA KANJANI? UMHLAHLANDLELA OSHESHAYO

INGABE UZIZWA KANJANI? UMHLAHLANDLELA OSHESHAYO

I-Cannabidiol (CBD) iyinhlanganisela ekhona esitshalweni se-cannabis (hemp). Njengamanje, uwoyela we-CBD uphakathi kwemikhiqizo ehamba phambili emakethe. Ngenxa yokuduma kwayo, imininingwane eminingi ephathelene nemikhiqizo ye-CBD inikezwa abathengi. Nokho, eminye imithombo yolwazi iyaphikisana. Ngenxa yalokho, abasebenzisi be-CBD bakhungatheka kakhulu futhi babe nokukhathazeka okwengeziwe nge-CBD nokusetshenziswa kwayo. Okunye ukungaboni ngaso linye kuvela emandleni e-CBD okubangela ukuphakama. Abantu badida imikhiqizo ye-CBD ne-THC. Nakuba zivela esitshalweni esifanayo, zihlukile. Ngakho-ke, amaqiniso mayelana namafutha e-cannabidiol kufanele asungulwe ukuze abathengi baqonde imiphumela yale mikhiqizo. Le bhulogi inikeza umhlahlandlela we uwoyela CBD nokuthi kwenza abantu bazizwe kanjani.

Iyini iCannabidiol (CBD)?

I-CBD iyinhlanganisela engeyona eyengqondo futhi engadaki etholakala kumakhambi ensangu. Umzimba womuntu unohlelo lwe-endocannabinoid oluthola futhi lukhiphe ama-cannabinoids emzimbeni wonke. Lapho usebenzisa imikhiqizo ye-CBD, uhlelo lwe-endocannabinoid luyasebenza. I-Tetrahydrocannabinol (THC) ingenye inhlanganisela ehlobene ne-cannabis. Le nhlanganisela ithinta ama-neurotransmitters ebuchosheni ngokunamathela ku-CB1 receptor. I-THC iphazamisa amaphethini okunyakaza, imizwa, umuzwa wesikhathi, amandla okugxila, kanye nenkumbulo. Imikhiqizo ye-cannabidiol ingatholakala ku-hemp noma insangu, iningi layo likhishwa ku-hemImikhiqizo eminingi ye-cannabidiol itholakala ku-hemp. Izitshalo zensangu cishe zine-THC engama-40%, kanti izitshalo ze-hemp zine-THC engaphansi kuka-0.3%. Lo mehluko ekusebenzeni kwe-THC ne-CBD kanye nokuhluka kwemvelaphi yezitshalo kuchaza ukuthi kungani imiphumela yako ihluka.

Ingabe i-CBD Iyalutha?

Ngemuva kokuthatha i-cannabidiol, ukuguqulwa komzimba kwanelisa abasebenzisi futhi ukugwema lo mkhiqizo kuba nzima. Kodwa-ke, lo mphumela awenzeki ngoba i-CBD iyalutha. Ngokwesayensi, i-cannabidiol ayilutha emazingeni amangqamuzana. Ezinye izifundo zibonisa ukuthi i-CBD isebenza ngokumelene notshwala, ama-opioid, kanye nezidakamizwa zikagwayi.

I-Cannabidiol Ikwenza Uzizwe Kanjani?

I-Cannabidiol ithatha isikhathi ukunqwabelana ohlelweni lomzimba futhi ithuthukise imiphumela. Abathengi bangase bangayizwa imiphumela ezinyangeni zokuqala noma amasonto okusetshenziswa kwemikhiqizo ye-cannabidiol nsuku zonke. Nokho, lokhu akubonisi ukungasebenzi kwayo. Izinzuzo zingase zibe nzulu futhi ziphindaphindeke ngokuhamba kwesikhathi. Abanye abantu bayehluleka ukuthola imiphumela baze bayeke ukusebenzisa i-CBD.

Kungani Kufanele Usebenzise I-CBD?

Abanye abantu bayazibuza ukuthi ngabe i-CBD ibangela ukuphakama uma isetshenziswa. Ngokwebhayoloji, i-cannabidiol isebenza nama-serotonin receptors nama-endocannabinoids emzimbeni. Uhlelo lwe-endocannabinoid lulawula inkumbulo, isifiso sokudla, i-metabolism, amasosha omzimba, ukuphatha ubuhlungu, ukukhiqiza kabusha, imizwa, kanye nengcindezi. Ngokuphambene, i-serotonin ilawula ukufunda komuntu nokuqonda imizwa, amaqiniso, nezinye izinqubo ezinjengokuhlanza. Ucwaningo lokuqala lukhombisa ukuthi abantu abaningi banezinkinga ngamasistimu angenhla. Ngisho nabantu ababonakala besebenza kakhulu futhi benempilo bangase babe nezinkinga ezifihliwe ngamazinga abo e-serotonin noma uhlelo lwe-endocannabinoid. Ngakho-ke, abantu abaningi bathuthukisa lezi zinqubo besebenzisa imikhiqizo ye-CBD.

Imikhiqizo ye-Cannabidiol Yenziwe Kanjani?

Abakhiqizi bakhipha uwoyela we-CBD ku-hemp. Lawa mafutha angaba ekwakhekeni kwe-spectrum ebanzi noma egcwele. I-cannabidiol egcwele i-spectrum iqukethe izinhlanganisela eziningi zezitshalo ze-hemp, okuhlanganisa i-terpenes, ama-cannabinoids, kanye nenani eliphakeme elingu-0.3 % iTHC. Abacwaningi babonise ukuthi i-cannabidiol isebenza kahle kakhulu uma kukhona i-THC, ama-flavonoid, nama-terpenes. Umphumela we-entourage obangelwa ukuhlanganisa lezi zinhlanganisela awunakuqhathaniswa. Ngalesi sizathu, ongoti abaningi bathatha imikhiqizo ye-cannabidiol egcwele-spectrum njengengcono kakhulu etholakalayo futhi enamandla kakhulu.

Ngesikhathi sokukhishwa kwe-cannabidiol ebanzi, abakhiqizi behlisa ubukhona be-THC kule nhlanganisela. Baqeda yonke i-THC emkhiqizweni wokugcina, kepha i-cannabidiol nezinye izingxenye ezibalulekile zesitshalo se-hemp zihlala. Abacwaningi abathile bacabanga ukuthi abasebenzisi bathola umphumela wokugqugquzela ngaphandle kokuba khona kwe-THC ohlelweni lomzimba. Nokho, ulwazi olwengeziwe luyadingeka ukuze kutholakale ukufaneleka kwalokhu kucatshangelwa. Imikhiqizo ye-cannabidiol ene-spectrum egcwele isebenza kangcono, kodwa imikhiqizo ebanzi ilungile uma kulindeleke ukuthi ihlolwe izidakamizwa.

Ingabe I-CBD Isemthethweni Futhi Iphephile?

Kusukela kuMthethosivivinywa Wepulazi ka-2018, i-CBD yagunyazwa, futhi amazinga e-THC abekelwe umkhawulo ezingeni eliphakeme lika-0.3%. Kodwa-ke, amakhambi ensangu avunyelwe ezingeni likahulumeni. Nakuba izifundazwe ezithile zigunyaze ukusetshenziswa nokukhula kwezinhlanganisela ezihlobene ne-THC, i-United States izibeka ngokwezigaba njengezinto zeSheduli 1. Mayelana nalokhu, azivunyelwe ukusetshenziswa kwezokwelapha. Ngokuphambene, i-cannabidiol ekhishwe yi-hemp ayinawo umkhawulo, kodwa abahlinzeki kufanele bagcine ama-invoyisi izinyanga ezingu-24. Ukukhiqizwa kwe-CBD kanye nezimboni ezikhulayo ze-hemp zihlala ngaphansi komthetho kahulumeni wobumbano. Kodwa-ke, kukhona okungaqondakali mayelana nokwengamela kukahulumeni, ukutholwa kocwaningo lwesayensi, nemithetho yezomthetho. Abathengi baphephile ukuthi bathenge futhi basebenzise imikhiqizo ye-CBD, kodwa abakhiqizi basengozini yokwephulwa komthetho.

Ucwaningo lubonisa ukuthi i-cannabidiol compound iphephile ngoba abathengi abaningi abatholi imiphumela emibi ngokusebenzisa i-CBD. Abasebenzisi abahlangabezana nemiphumela engemihle ekukhishweni kwe-cannabidiol bahlangabezana nokucasuka, ukukhathala, nesicanucanu isikhathi esifushane. Ngokuphawulekayo, i-CBD isebenzisana nemithi ethile. Ngakho-ke, thintana nodokotela wakho ngaphambi kokusebenzisa uwoyela we-CBD, ikakhulukazi uma ungaphansi kwemithi. Imikhiqizo ye-CBD engcolile iyingozi empilweni yomuntu. Ngakho-ke, qinisekisa ukuthi inkampani oyithengayo iqhuba ukuhlolwa komuntu wesithathu. Lawa ma-laboratories ahlola amandla kanye namazinga okuhlanzeka. Ilebhu iqinisekisa ukuthi imikhiqizo ayinakho ukungcola okuyingozi njengezinsimbi ezisindayo nezibulala-zinambuzane.

Isiphetho

I-Food and Drugs Administration, i-FDA, ikugunyaze kuphela ukusetshenziswa kwe-Epidiolex, umuthi ofakwe ku-CBD, wesifo sokuwa ezinganeni ezingaphansi konyaka owodwa. Umzimba awukagunyazi eminye imikhiqizo ye-CBD. Ukwengeza, ukuthengisa le mikhiqizo enamalebula ezithako zokudla noma ukuwahlanganisa ekudleni akukho emthethweni. Imiphumela ye-Cannabidiol iyahluka kuye ngabathengi. Kuthatha izinsuku noma amaviki athile ukuchayeka njalo kwe-CBD ukuze uthole imiphumela ebalulekile. Lapho ukhetha okukhishiwe, qiniseka ukuthi uthenga imikhiqizo ye-CBD evela eceleni ehloliwe kanye nesezingeni eliphezulu. Futhi, thintana nodokotela ngaphambi kokusebenzisa imikhiqizo ye-CBD, ikakhulukazi uma ungaphansi kwemithi.

Uchwepheshe wezempilo yengqondo
MS, University of Latvia

Ngiqiniseka ngokujulile ukuthi isiguli ngasinye sidinga indlela eyingqayizivele, yomuntu ngamunye. Ngakho-ke, ngisebenzisa izindlela ezahlukene zokwelashwa kwengqondo emsebenzini wami. Phakathi nezifundo zami, ngathola isithakazelo esijulile kubantu bebonke kanye nenkolelo yokungahlukaniseki kwengqondo nomzimba, kanye nokubaluleka kwempilo yemizwa empilweni yomzimba. Ngesikhathi sami sokuphumula, ngijabulela ukufunda (umlandeli omkhulu wama-thrillers) nokuqwala izintaba.

Okwakamuva okuvela ku-CBD